Clinical Trial: Evaluation of Anti-inflammatories in the Reduction of Bite Reactions

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Evaluation of Topical Ibuprofen and Steroid in the Reduction of Local Reactions and Symptoms From an Aedes Aegypti Mosquito Bite

Brief Summary: The purpose of this study is to evaluate two separate antiinflammatory products for the relief of symptoms through suppression of the immunological and inflammatory response following a mosquito bite. The investigators have selected ibuprofen gel as a NSAI formulation and 0.05% Clobetasone butyrate as a steroid cream with their appropriate physical matched placebo products.

Detailed Summary:
Sponsor: London School of Hygiene and Tropical Medicine

Current Primary Outcome: size of wheal, flare in mm [ Time Frame: 90 minutes ]

The statistical difference between active and placebo agent on bite reaction measured as size of wheal, flare in mm and itching measured on a visual scale recorded by the subject.ct.


Original Primary Outcome: Same as current

Current Secondary Outcome: Subjective pain and itching [ Time Frame: 90 minutes ]

Subjective record of pain and itching recorded on a visual scale


Original Secondary Outcome: Same as current

Information By: London School of Hygiene and Tropical Medicine

Dates:
Date Received: October 12, 2011
Date Started: November 2012
Date Completion:
Last Updated: March 30, 2015
Last Verified: March 2013