Clinical Trial: Guided Self-Help for Binge Eating Disorder

Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Interventional

Official Title: Comparison of Integrative Response Therapy and Cognitive Behavioral Therapy Guided Self-Help for Binge Eating Disorder

Brief Summary: The proposed study will employ a randomized design to evaluate the efficacy of two group-based guided self-help treatments: Integrative Response Therapy (IRT) and Cognitive Behavior Therapy Guided Self-Help, a treatment of known efficacy, in group-format (CBT-GSHg) in the treatment of Binge Eating Disorder (BED), and explore (1) moderators and mediators of treatment, (2) the relative cost-effectiveness of the two treatments, and (3) between group differences on secondary measures (e.g., eating disorder and general psychopathology).

Detailed Summary:

The focus of this proposal is on BED among an adult population. Guided self-help treatments (GSH) for BED appear promising and may be more readily disseminated than efficacious specialty treatments such as Cognitive Behavioral Therapy (CBT) and Interpersonal Psychotherapy (IPT) given the latter's administration costs and time requirements. The proposed study uses a new group-based, guided self-help BED treatment called Integrative Response Therapy (IRT). IRT is primarily based upon the affect regulation theory of binge eating (e.g., binge eating is an attempt to alter distressing emotional states), while adding cognitive restructuring techniques. IRT teaches effective ways to cope with aversive emotions and reframe faulty cognitions while reducing vulnerabilities that are likely to lead to problematic emotional responding & cognitions such as physical needs (e.g., hunger, sleep deprivation), interpersonal conflict, and, when possible, unpleasant external events. IRT's primary goal is to significantly decrease episodes of binge eating and associated eating disorder pathology.

CBT-GSH is a frequently used manual-based form of GSH that has demonstrated efficacy. CBT, based on the restraint model, intervenes via behavioral techniques to replace restrained eating with more regular eating patterns and cognitive techniques to restructure an individual's problematic thoughts that over-evaluate shape and weight. Research literature indicates that CBT-GSH is a viable self-help BED treatment that appears to be superior to wait-list control conditions, equivalent to IPT, a specialty treatment, and superior to Behavioral Weight Loss treatment at 2-year follow-up. There are then, a number of reasons for further research on GSH in general and CBT-gsh specifically.

The proposed study will lay the groundwork for identifying which GSH t
Sponsor: Stanford University

Current Primary Outcome: number of binge days over the previous 28 days [ Time Frame: 16 weeks post-treatment ]

Assessed via the Eating Disorder Examination


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • emotion driven urges to eat [ Time Frame: 16 weeks post-treatment, 6 and 12 month follow-up ]
    Assessed via the Emotional Eating Scale
  • adaptation time intervals and response accuracy for emotion related stimuli [ Time Frame: 16 weeks post-treatment ]
    Assessed via the Emotion Conflict Adaptation Task
  • depression [ Time Frame: 16 weeks post-treatment, 6 and 12 month follow-up ]
    Assessed via the Beck Depression Inventory
  • self-esteem [ Time Frame: 16 weeks post-treatment, 6 and 12 month follow-up ]
    Assessed via the Rosenberg Self-Esteem Scale
  • quality of life [ Time Frame: post-treatment, 6 and 12 month follow-up ]
    Assessed via the Quality of Well-Being Scale
  • use of health services [ Time Frame: at (approximately) 1 month intervals throughout 16 week intervention (4 times total) ]
    Assessed via the Health Care Diary


Original Secondary Outcome: Same as current

Information By: Stanford University

Dates:
Date Received: January 14, 2011
Date Started: June 2010
Date Completion: May 2015
Last Updated: May 13, 2013
Last Verified: May 2013