Clinical Trial: Risk Factors Associated With Binge Drinking Behaviors Among College Students

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: AlcoholPredict: Neuropsychology, Brain Imaging and Genetic Polymorphisms in Binge Drinking

Brief Summary: The purpose of this study is to specify the psychological, cognitive, neuro-functional and genetic profile associated with binge drinker behaviors among young adults. Results will help identifying more precisely vulnerability factors associated with this pattern of alcohol consumption and guiding prevention efforts.

Detailed Summary: Binge drinking behavior is characterised by speed of drinking on a particular occasion, frequency of drunkenness during the most recent six month period, and the percentage of times getting drunk when drinking. The prevalence of weekly binge drinking among European Union drinkers in 2009 was reported to be 28% of the student population, and 33% among all young people aged 15-24. The consequences of this behavior are multiple and often dramatic, they include: academic failure, violent acts, rape, domestic or road accidents. The study aims to identify vulnerability factors associated with binge drinking. The protocol explores the psychological (personality), neuropsychological (executive functions, memory), genetic (snp polymorphisms) and neuro-anatomical (fMRI) patterns associated with binge drinking behavior.
Sponsor: CHU de Reims

Current Primary Outcome:

  • Neuropsychological test : Mini International Neuropsychiatric Interview (M.I.N.I) [ Time Frame: day 1 ]
  • Neuropsychological test : Wisconsin Card Sorting Test (WCST) [ Time Frame: V2(3 weeks later) ]
  • Genetics tests (Single Nucleotide Polymorphism) [ Time Frame: V2(3 weeks later) ]
  • MRI - signal BOLD (" Blood Oxygen Level Dependant "). [ Time Frame: V3(up to 2 month) ]
  • Neuropsychological test : Family Informant Schedule and Criteria (FISC) [ Time Frame: day 1 ]
  • Neuropsychological test : Alcohol Use Questionnaire [ Time Frame: day 1 ]
  • Neuropsychological test :Trail Making Test, partie A et B [ Time Frame: V3(up to 2 month) ]
  • Neuropsychological test : Plus/Minus Test [ Time Frame: V3(up to 2 month) ]
  • Neuropsychological test :Go/No-Go [ Time Frame: V3(up to 2 month) ]


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: CHU de Reims

Dates:
Date Received: May 12, 2016
Date Started: February 2015
Date Completion: February 2017
Last Updated: June 3, 2016
Last Verified: June 2016