Clinical Trial: Influence of Acid Reflux on Stromal Epithelial Interaction in Barrett's Esophagus
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: Influence of Acid Reflux on Stromal Epithelial Interaction in Barrett's Esophagus
Brief Summary:
The purpose of this study is to determine the association between acid reflux and cell changes in Barrett's esophagus.
Specific aim 1: To test the hypothesis that controlled acid reflux is associated with lesser degree of stromal activation.
Specific aim 2: To test the hypothesis that stromal fibroblast derived growth factors drive BE epithelial proliferation.
Detailed Summary:
Sponsor: Mayo Clinic
Current Primary Outcome: activated myofibroblasts [ Time Frame: 6 months ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Mayo Clinic
Dates:
Date Received: January 20, 2011
Date Started: October 2008
Date Completion:
Last Updated: May 3, 2013
Last Verified: May 2013