Clinical Trial: Effectiveness of the Quotient® ADHD Assessment in a System of Care

Study Status: Terminated
Recruit Status: Terminated
Study Type: Interventional

Official Title: Effectiveness of the Quotient® ADHD Assessment in a System of Care

Brief Summary: The study goal is to examine whether the use of an objective computerized neuroassessment (the Quotient System) for Attention-Deficit/Hyperactivity Disorder (ADHD) is related to improved outcomes among pediatric patients being assessed and treated for ADHD.

Detailed Summary: This study is a randomized, controlled trial using a 2-phase data collection. The first phase is the initial assessment for ADHD and includes all patients eligible to be assessed for ADHD as determined by their clinician in the course of usual care. The baseline measurements will be used to compare groups at baseline, and also for longitudinal analyses of medication management. Patients are randomized at this point. Patients in both treatment arms who then receive an ADHD diagnosis and who start medication for ADHD will be eligible for the second phase of the study: three follow-up assessments over six months. Patients who do not have an ADHD diagnosis will not continue in the study, and will be treated by their clinician as usual.
Sponsor: Kaiser Permanente

Current Primary Outcome: Time to therapeutic dose [ Time Frame: One month, 3 month and six month follow ups ]

The primary outcome measure will be change in the dose of ADHD medication as measured across three followup time points, comparing a Usual Care group and a Quotient test group. The hypothesis is that patients who receive the Quotient test (the computerized neuroassessment) will reach a stable therapeutic dose of ADHD medication more quickly, compared to Usual Care.


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • ADHD Symptomatology [ Time Frame: 1, 3 and 6 months post baseline ]
    ADHD symptomatology measured by the SNAP-IV
  • Academic Performance [ Time Frame: Baseline and Six Months ]
    Academic performance will be measured by student report cards, and converted to a standardized scale
  • Persistence in Care [ Time Frame: Baseline to Six Months ]
    Use of pediatric health care services
  • Medication Adherence [ Time Frame: Baseline to six months ]
    Sustained use of ADHD medication
  • Satisfaction with care [ Time Frame: Six months ]
    Likert scale single item measure of how satisfied the pediatric patient's parent was with care received
  • Other health services use [ Time Frame: Baseline to six months ]
    Use of healthcare services outside of pediatrics, including the emergency room and psychiatric services.


Original Secondary Outcome:

  • ADHD Symtomatology [ Time Frame: 1, 3 and 6 months post baseline ]
    ADHD symptomatology measured by the SNAP-IV
  • Academic Performance [ Time Frame: Baseline and Six Months ]
    Academic performance will be measured by student report cards, and converted to a standardized scale
  • Persistence in Care [ Time Frame: Baseline to Six Months ]
    Use of pediatric health care services
  • Medication Adherence [ Time Frame: Baseline to six months ]
    Sustained use of ADHD medication
  • Satisfaction with care [ Time Frame: Six months ]
    Likert scale single item measure of how satisfied the pediatric patient's parent was with care received
  • Other health services use [ Time Frame: Baseline to six months ]
    Use of healthcare services outside of pediatrics, including the emergency room and psychiatric services.


Information By: Kaiser Permanente

Dates:
Date Received: March 13, 2014
Date Started: March 2014
Date Completion:
Last Updated: March 4, 2016
Last Verified: March 2016