Clinical Trial: Treatment of Recurrent Aphthous Stomatitis With Er,Cr:YSGG Laser Irradiation

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Treatment of Recurrent Aphthous Stomatitis With Er,Cr:YSGG Laser Irradiation: A Randomized Controlled Clinical Study

Brief Summary: The aim this study was to investigate the efficacy of Er,Cr:YSGG laser irradiation in reducing pain and on healing rate of recurrent aphthous stomatitis 40 patients with RAS were included to the study. For each patient, ulceration were randomly assigned to the test or the control group. In test group RAS irradiated with Er,Cr:YSGG laser using non-contact mode. In the placebo group, the same Er,Cr:YSGG laser without laser emission was used. Pain was evaluated with visual analog scale (VAS). Healing of RAS (HRAS) was graded by a clinician.

Detailed Summary:
Sponsor: Near East University, Turkey

Current Primary Outcome: Reduce of Visual Analog Scale (VAS) scores [ Time Frame: 10 days ]

Patients were asked to record their pain and discomfort level for each stomatit by marking a point on a 10 cm visual analog scale (VAS).


Original Primary Outcome: Same as current

Current Secondary Outcome: The healing of recurrent aphthous (HRAS) scores [ Time Frame: 10 days ]

The healing of RAS (HRAS) were evaluated:at the follow-up sessions by the investigator on a four-point scale (range 1-4). Grade 1 represented totally healing, grade 2 moderate healing (more than 50% of RAS was epithelialized and healed), grade 3 slightly healing (less than 50% of RAS was epithelialized and healed) and grade 4 no healing.


Original Secondary Outcome: Same as current

Information By: Near East University, Turkey

Dates:
Date Received: September 28, 2016
Date Started: January 2015
Date Completion:
Last Updated: October 4, 2016
Last Verified: October 2016