Clinical Trial: Evaluation of Therapeutic Effect of 0.5 mg Colchicine and 5 mg Prednisolone on Oral Aphthae

Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Interventional

Official Title: Evaluation of Therapeutic Effect of 0.5 mg Colchicine and 5 mg Prednisolone on Oral Aphthae

Brief Summary: The purpose of this study is to determine whether low doses of prednisolone, or colchicine are effective in the treatment of oral aphthae.

Detailed Summary: Treatment of recurrent aphthous stomatitis (RAS) remains, to date, empirical and non-specific. The main goals of therapy are to minimize pain and functional disabilities as well as decrease inflammatory reactions and frequency of recurrences.
Sponsor: Mashhad University of Medical Sciences

Current Primary Outcome: frequency of ulcers [ Time Frame: 1 year ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Mashhad University of Medical Sciences

Dates:
Date Received: July 24, 2008
Date Started: May 2007
Date Completion:
Last Updated: July 28, 2008
Last Verified: July 2008