Clinical Trial: The Clinical Efficacy of DFPP in Patients With AAGN
Study Status: Terminated
Recruit Status: Terminated
Study Type: Interventional
Official Title: A Prospective, Controlled Study of Double Filtration Plasmapheresis (DFPP) in Patients With Antineutrophil Cytoplasmic Autoantibody Associated Glomerulonephritis (AAGN)
Brief Summary: The clinical efficacy of double filtration plasmapheresis(DFPP) in patients with antineutrophil cytoplasmic autoantibody associated glomerulonephritis(AAGN).
Detailed Summary: This is a single center, prospective, randomized,controlled study to compare the clinical efficacy of double filtration plasmapheresis (DFPP) combined with intravenous cyclophosphamide (IV-CTX) pulse therapy versus IV-CTX pulse therapy in patients with antineutrophil cytoplasmic autoantibody associated glomerulonephritis(AAGN).
Sponsor: Zhi-Hong Liu, M.D.
Current Primary Outcome: the renal recovery rate [ Time Frame: 3 months ]
Original Primary Outcome: Same as current
Current Secondary Outcome: kidney survival [ Time Frame: 12 months ]
Original Secondary Outcome: Same as current
Information By: Nanjing University School of Medicine
Dates:
Date Received: June 3, 2014
Date Started: June 2014
Date Completion: November 2018
Last Updated: May 14, 2017
Last Verified: May 2017