Clinical Trial: Changes in Adrenal Hormones During Adrenal Radiofrequency Ablation

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Changes in Adrenal Hormones During Adrenal Radiofrequency Ablation

Brief Summary: The purpose of this study is to evaluate changes in adrenal hormones during adrenal radiofrequency (RF) ablation.

Detailed Summary: Adrenal radiofrequency (RF) ablation has been increasingly used for the treatment of unresectable adrenal tumors. But one of the major complication is a increase in blood pressure. Hormonal release during RF ablation is considered the cause of hypertension. But there has been no evidence that adrenal hormones affects changes in blood pressure. In this prospective study, we evaluate the changes in adrenal hormones during RF ablation and clarify the cause of hypertensive crisis.
Sponsor: Mie University

Current Primary Outcome:

• Increase in Catecholamine [ Time Frame: One day ]
• Serum Cathecholamine Levels [ Time Frame: around one year ]
• Number of Participants With Hypertension During Adrenal or Non-adrenal Radiofrequency Ablation [ Time Frame: 1 week ]
  Blood pressure was monitored during radiofrequency (RF) ablation. The frequency of hypertension (systolic blood pressure of more than 200 mmHg) was evaluated and compared between the adrenal and non-adrenal (RF ablation other than adrenal gland) RF ablation groups.

Original Primary Outcome: Increase in Catecholamine [ Time Frame: One day ]

Current Secondary Outcome: Increase in Cortisol [ Time Frame: 1 day ]

Original Secondary Outcome: Same as current

Information By: Mie University

Dates:
Date Received: October 16, 2009
Date Started: October 2009
Date Completion:
Last Updated: April 6, 2015
Last Verified: April 2015