Clinical Trial: REal World Information on Cardiovascular Drug Management Patterns in Acute Coronary Syndrome paTients

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: REal World Information on Cardiovascular Drug Management Patterns in Acute Coronary Syndrome paTients

Brief Summary: RE-ACT is a national, multi-centre, observational, prospective, longitudinal cohort study which will include patients hospitalized for ACS within 24 hours of symptom onset and who have a final diagnosis of ST-segment elevation myocardial infarction (STEMI) or non-ST-segment elevation myocardial infarction (NSTEMI). This study aims to describe the short-term (at the end of the first month after index event) antithrombotic management patterns in a "real-life" setting for patients hospitalized with an acute coronary syndrome.

Detailed Summary:
Sponsor: AstraZeneca

Current Primary Outcome: Short-term antithrombotic management patterns (AMPs) in a real-life setting for patients hospitalized with an ACS [ Time Frame: Baseline ]

Descriptive statistics will be calculated for this outcome measure using frequency tables (n, frequency and percentage). Antithrombotic management patterns will be grouped taking into account only the different treatment options shown by the descriptive analysis.


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Variations in the acute clinical management strategies and AMPs. [ Time Frame: Baseline ]
    Descriptive statistics will be calculated for this outcome measure using frequency tables (n, frequency and percentage).
  • Impact of the different AMPs on quality of life at discharge from hospital (using EuroQoL-5D). [ Time Frame: Baseline ]
    Descriptive statistics will be calculated for this outcome measure using frequency tables (n, mean, median, standard deviation, minimum and maximum)
  • Impact of the different AMPs on quality of life at the end of the first month after discharge from the hospital (using EuroQoL-5D). [ Time Frame: At the end of the first month after index event ]
    Descriptive statistics will be calculated for this outcome measure using frequency tables (n, mean, median, standard deviation, minimum and maximum)
  • Determinants of AMP choices (i.e. patient's characteristics, hospital characteristics, coronary intervention strategies and type of coronary stents used) [ Time Frame: Baseline ]
    Descriptive statistics will be calculated for this outcome measure using frequency tables (n, frequency and percentage).


Original Secondary Outcome: Same as current

Information By: AstraZeneca

Dates:
Date Received: November 18, 2013
Date Started: February 2014
Date Completion:
Last Updated: November 13, 2014
Last Verified: November 2014