Clinical Trial: Efficacy of Lactobacillus GG (LGG) in Children With Abdominal Pain

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: The Use of Lactobacillus gg in Functional Abdominal Pain in Children: a Double-blind Randomized Control Trial

Brief Summary: Probiotics play an important role in preventing overgrowth of potentially pathogenic bacteria and maintaining the integrity of the gut mucosal barrier. The beneficial effects of probiotics have been previously studied in adult patients with IBS. Even though most of the studies demonstrate efficacy, other studies do not support these observations. Few studies addresses the efficacy of probiotics in children with IBS. The goal of the present study was to determine whether oral administration of the probiotic Lactobacillus GG under randomized, double-blind, placebo-controlled conditions would improve symptoms of children with abdominal pain.

Detailed Summary:
Sponsor: University of Bari

Current Primary Outcome: The primary outcome measure was defined as reduction of pain (both number of episodes and intensity) at the end of the intervention. [ Time Frame: 12 weeks and 20 weeks ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: University of Bari

Dates:
Date Received: April 2, 2009
Date Started: December 2004
Date Completion:
Last Updated: January 31, 2011
Last Verified: April 2009