Clinical Trial: Deep Brain Stimulation of the Nucleus Accumbens as a Novel Treatment in Severe Opioid Addiction
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: Deep Brain Stimulation of the Nucleus Accumbens as a Novel Treatment in Severe Opioid Addiction
Brief Summary:
The main objective of this study is to assess the efficacy of bilateral deep brain stimulation (DBS) of the Nucleus accumbens (NAc) as a novel treatment in severe opioid addiction. The included patients have been treated so far with a substitute in form of methadone.
Our hypothesis is that bilateral DBS of the NAc will significantly reduce the craving for heroin and thus enable the patients to decrease their Levomethadone-dosage substantially.
Detailed Summary:
Sponsor: Jens Kuhn
Current Primary Outcome: Reduction of Levomethadone [ Time Frame: seven month ]
Original Primary Outcome: Same as current
Current Secondary Outcome: Drug seeking, goal directed behavior, Craving, Psychological components Laboratory parameters in the urine (parallel consumption of other drugs) [ Time Frame: seven month ]
Original Secondary Outcome: Same as current
Information By: University of Cologne
Dates:
Date Received: November 19, 2010
Date Started: January 2011
Date Completion: December 2017
Last Updated: December 6, 2016
Last Verified: December 2016