Clinical Trial: Spanish Bacteriemia Cohort 2016: Epidemiology, Clinical Management and Prognosis Factors
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational
Official Title: Spanish Cohort of Bacteriemias 2016: Epidemiology, Clinical Management and Prognostic Factors at Diagnosis.
Brief Summary:
Bacteremia
The Hypothesis of the study are the followings:
- To demonstrate relevant epidemiologic and clinical changes with potentially impact in the management and prognosis of the patients with bacteremia.
- Since the diagnosis and management is heterogeneous between centers, we could identify a scenario to improve.
- To identify quality indicators in the management of bacteremia.
- To demonstrate that some interventions made by Bacteremia Team pose relevant impact in the prognosis of bacteremia.
Detailed Summary:
Sponsor: Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Current Primary Outcome: Epidemiology and prognostic factors of bacteremia episodes. [ Time Frame: From day 0 to day 30 ]
- Global incidence and per type of acquisition.
- Global etiology and per type of acquisition.
- Frequency of multiresistant and emerging microorganism.
- Source of bacteremia.
- Clinical severity of presentation.
- Clinical failure, mortality at day 7, mortality at day 30, recurrence, length of stay and re-admission at hospital.
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Clinical management of patients with bacteremia during the episode. [ Time Frame: From day 0 to day 30 ]
- Antibiotic therapy used during the episodes (empirical and targeted).
- Non antibiotic therapy/support therapy used during the episode.
- Frequency of focus search and adequate control.
- Differences in the management between types of services, wards and hospitals. [ Time Frame: From day 0 to day 30 ]Comparison between different services and hospital wards of variables regarding on the management of episodes.
- Influence of clinical management in the prognosis. [ Time Frame: From day 0 to day 30 ]- Identifying prognostic factors related with mortality, clinical failure and recurrence.
- Developing and validating a predictive model for early and late mortality. [ Time Frame: From day 0 to day 30 ]- Developing and validating a predictive model for mortality based in prognostic factors related with mortality.
- Quality indicators in the management of bacteremia. [ Time Frame: From day 0 to day 30 ]- Identifying quality indicators in the management of episodes of bacteremia.
- Interventions made by Bacteremia Team. [ Time Frame: From day 0 to day 30 ]
- Frequency and type of interventions made by Bacteremia Teams.
- Impact of these interventions in the management and prognosis of episodes.
Original Secondary Outcome: Same as current
Information By: Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Dates:
Date Received: April 5, 2017
Date Started: October 2016
Date Completion: January 2018
Last Updated: May 8, 2017
Last Verified: May 2017