Clinical Trial: GnRHa Combined With hCG and hMG for Treatment of Patients With Non-obstructive Azoospermia
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: GnRHa Combined With hCG and hMG for Treatment of Patients With Non-obstructive Azoospermia: A Single-center Prospective Study in China
Brief Summary: Preliminary reports showed that hormonal treatment may improve the chance of retrieving viable testicular sperm from men with NOA. It was generally believed that gonadotrophin treatment would be ineffective in the presence of high plasma levels of endogenous gonadotrophin.The purpose of this study is to determine whether GnRHa(gonadotropin-releasing hormone agonist) combined with hCG(human chorionic gonadotropin) and hMG(human menopausal gonadotropin) are effective in the treatment of non-obstructive azoospermia.
Detailed Summary:
Sponsor: Jinling Hospital, China
Current Primary Outcome: Sperm retrieval rate (SRR) [ Time Frame: 4 months ]
Original Primary Outcome: Sperm retrieval rate (SRR) [ Time Frame: 3 months ]
Current Secondary Outcome: Hormonal profile [ Time Frame: 9 months ]
Original Secondary Outcome: Hormonal profile [ Time Frame: 6 months ]
Information By: Jinling Hospital, China
Dates:
Date Received: August 29, 2015
Date Started: December 2015
Date Completion: December 2017
Last Updated: August 1, 2016
Last Verified: August 2016