Clinical Trial: Exercise as an Adjuvant to Aphasia Therapy
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Exercise as an Adjuvant to Aphasia Therapy
Brief Summary: The purpose of the study is to reveal if individuals who participate in aerobic activity demonstrate improvement in language abilities than patients who do not participate in aerobic activity.
Detailed Summary: The objective of this research project is to reveal if individuals who participate in aerobic activity demonstrate greater improvement in language abilities with treatment than patients who do not participate in aerobic activity. As secondary objectives, we will determine if there is a direct relationship between either brain efficiency or increases in Brain Derived Neurotrophic Factor (BDNF) after exercise and higher learning rates in aphasia.
Sponsor: VA Office of Research and Development
Current Primary Outcome: change in picture naming abilities [ Time Frame: administered before and after each of two, two week aphasia therapy blocks ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- change in serum BDNF levels with exercise [ Time Frame: six samples collected over a 16 week period ]
- efficiency of neural processing [ Time Frame: fMRI administered before and after each of two, two week aphasia therapy blocks ]
Original Secondary Outcome: Same as current
Information By: VA Office of Research and Development
Dates:
Date Received: April 28, 2010
Date Started: July 2009
Date Completion:
Last Updated: February 6, 2017
Last Verified: February 2017
