Clinical Trial: Long-term Behavior Change - 1

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Behavior Change: Reinforcement Schedule Effects

Brief Summary: The purpose of this study is to determine if different reinforcement procedures (i.e., schedules) produce different patterns of long-term abstinence from methamphetamine. We anticipate that the three contingency management conditions will promote longer periods of abstinence in the year following treatment relative to the standard control group. Furthermore, we predict that the intermittent reinforcement procedures will produce longer periods of continued abstinence (i.e., long-term behavior change) in the year following treatment than the continuous reinforcement procedure. Finally, we predict that the intermittent unpredictable schedule will produce longer lasting behavior change than the intermittent predictable schedule. Methamphetamine use will be measured using urine toxicology and self-report of methamphetamine use.

Detailed Summary: Briefly the four study conditions are: (1) standard treatment which consists of 16 weeks of psychosocial treatment, (2) continuous contingency management which consists of 16 weeks of psychosocial treatment with a contingency management procedure in effect during the first twelve weeks in which vouchers are made available after each provision of a methamphetamine-negative urine test, (3) intermittent predictable contingency management which consists of 16 weeks of psychosocial treatment with a contingency management procedure in effect during the first twelve weeks in which vouchers are available after the provision of every three consecutive methamphetamine-negative urine samples, and (4) intermittent unpredictable contingency management which consists of 16 weeks of psychosocial treatment with a contingency management procedure in effect during the first twelve weeks in which vouchers are available on one day each week (randomly selected after the first week) for the provision of methamphetamine-negative urine samples provided all urine samples since delivery of the last reinforcer were also methamphetamine negative.
Sponsor: Friends Research Institute, Inc.

Current Primary Outcome:

• Methamphetamine Use During Intervention [ Time Frame: 3x/week for 16 weeks ]
  Drug use measured by urine toxicology conducted by on site Enzyme-multiplied immunoassay technique (EMIT) assay over time.
• Methamphetamine Use, Measured by Number of Consecutive Days of Abstinence [ Time Frame: 16 Weeks ]
  Drug use measured by urine toxicology conducted by on site EMIT assay and added up to obtain how many days of consecutive abstinence were observed for each individual
• Methamphetamine Use, Follow-Up [ Time Frame: 1x/month for 4 months ]
  Drug use measured by urine toxicology conducted by on site EMIT assay over time

Original Primary Outcome: Methamphetamine Use during and following intervention

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Friends Research Institute, Inc.

Dates:
Date Received: September 8, 2005
Date Started: December 2004
Date Completion:
Last Updated: August 11, 2015
Last Verified: August 2015