Clinical Trial: Effectiveness of Telescopic Magnification in the Treatment of Amblyopia

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Effectiveness of Telescopic Magnification in the Treatment of Amblyopia

Brief Summary: Amblyopia is a visual impairment of one eye that results from disuse of that eye during early brain development. The standard treatment for amblyopia consists of patching or pharmacological penalization of the sound eye. Unfortunately, approximately 50% of amblyopic children do not respond to these therapies, with poor compliance being a major factor in treatment failure. One new treatment strategy involves patching the sound eye while using a telescopic device on the amblyopic eye to magnify the images formed in the amblyopic eye. Children were randomized to receive either daily patching of the sound eye for 30 minutes only (patching only group), or daily patching of the sound eye for 30 minutes plus simultaneous use of a telescopic device by the amblyopic eye during patching (patching plus telescope group).

Detailed Summary: The goal of the present investigation was to conduct a prospective randomized clinical study to further evaluate the effectiveness of telescopic magnification plus patching vs patching alone on different types of amblyopia in patients who had failed previous treatment.
Sponsor: The Hospital for Sick Children

Current Primary Outcome: The best corrected logMAR visual acuity score of the amblyopic eye. [ Time Frame: 17 weeks ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Visual acuity of at least 0.2 logMAR (20/30) and/or improvement of at least 0.2 logMAR from baseline in the amblyopic eye. [ Time Frame: 17 weeks ]

Original Secondary Outcome: Same as current

Information By: The Hospital for Sick Children

Dates:
Date Received: September 1, 2009
Date Started: December 2007
Date Completion:
Last Updated: August 26, 2013
Last Verified: August 2013