Clinical Trial: Study of the Prognostic Value of Musculoskeletal Ultrasound in Adults With Chikungunya

Study Status: Active, not recruiting
Recruit Status: Active, not recruiting
Study Type: Observational

Official Title: Study of the Prognostic Value of Musculoskeletal Ultrasound in Adults With Chikungunya

Brief Summary: Chikungunya is a viral disease transmitted by mosquitoes whose clinical feature is the early joint damage. Approximately 8% of patients have chronic arthropathy resembling to the rheumatoid polyarthritis. The EchoCHIK study we propose is in the context of the epidemic in Martinique which began in January 2014. It should give a better understanding of arthritis and juxtaarticular of CHIK and look for signs that may allow ultrasound predict the evolution of chronic arthropathy of CHIK.

Detailed Summary:
Sponsor: University Hospital Center of Martinique

Current Primary Outcome: Presence of sonographic signs observed during the initial scan: periarticular infiltration, effusion, positive Doppler, erosions. [ Time Frame: enrollement visit ]

Progression to chronic form defined by the persistence or recurrence of muscle symptoms (myalgia) and joints (arthralgia, arthritis) more than two months after the onset of symptoms of acute phase.


Original Primary Outcome: Same as current

Current Secondary Outcome: Presence of clinical and sonographic signs observed at each visit: arthralgia, arthritis clinics, periarticular infiltration, effusion, positive Doppler erosions. [ Time Frame: 1 month, 3 month, 6 month and 12 month after the first symptoms of infection by chikungunya virus ]

Original Secondary Outcome: Same as current

Information By: University Hospital Center of Martinique

Dates:
Date Received: October 29, 2014
Date Started: July 2014
Date Completion: January 2016
Last Updated: July 27, 2015
Last Verified: July 2015