Clinical Trial: A Study of Vitamin D in Subjects With Alopecia Areata

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: A Pilot Study of Vitamin D in Subjects With Alopecia Areata

Brief Summary: The objective of this study is to assess the parathyroid-vitamin D-calcium axis in subjects with alopecia areata. The hypothesis behind this study is that hypovitaminosis D might contribute to the pathogenesis of alopecia areata.

Detailed Summary: Alopecia Areata (AA) is a T-Cell mediated, non-scarring, polygenic, autoimmune disease of the hair follicle. It has been reported to be associated with other autoimmune diseases, especially autoimmune thyroid disease and vitiligo. It is more common in females. Recently, vitamin D deficiency has been claimed to contribute to the pathogenesis of multiple autoimmune disease. There is a strong inverse correlation between the level of 25-hydroxyvitamin D levels and the autoimmune disease in adolescents.
Sponsor: Avera McKennan Hospital & University Health Center

Current Primary Outcome: Vitamin D levels will be reported in subjects and correlated with the calcium and parathyroid levels. [ Time Frame: Initial clinic visit (day 1) ]

This study consists of a single clinic visit. After subject has completed the informed consent process and meets eligibility criteria, a blood sample will be collected. Lab results from this one-time lab draw will be evaluated.


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Avera McKennan Hospital & University Health Center

Dates:
Date Received: January 6, 2011
Date Started: August 2009
Date Completion:
Last Updated: July 6, 2011
Last Verified: July 2011