Clinical Trial: From Uncomplicated Alcoholism to Korsakoff's Syndrome

Study Status: Completed
Recruit Status: Unknown status
Study Type: Interventional

Official Title: From Uncomplicated Alcoholism to Korsakoff's Syndrome: Clinical, Genetic, Neuropsychological and Brain Examinations

Brief Summary: This research project aims to identify factors that contribute to the heterogeneity observed in neuroradiological and neuropsychological signs of chronic alcoholism. The investigators overarching hypothesis is that the heterogeneity of alcoholic consequences on brain structure and metabolism, and cognition is mainly related to individual differences in pattern of alcohol use, gene pool, nutritional status and history of withdrawal symptoms.

Detailed Summary:
Sponsor: University Hospital, Caen

Current Primary Outcome: Evidence of brain dysfunctioning measured by neuropsychological testing and brain examination(MRI and PET) [ Time Frame: one year ]

Original Primary Outcome: Same as current

Current Secondary Outcome: treatment outcomes (sobriety or relapse) [ Time Frame: one year ]

Original Secondary Outcome: Same as current

Information By: University Hospital, Caen

Dates:
Date Received: October 18, 2011
Date Started: January 2012
Date Completion: January 2015
Last Updated: April 8, 2014
Last Verified: April 2014