Clinical Trial: Preclinical Study Towards an Immunotherapy in Adrenocortical Carcinoma

Study Status: Active, not recruiting
Recruit Status: Active, not recruiting
Study Type: Observational [Patient Registry]

Official Title: Präklinische Studie Zur Etablierung Einer Immuntherapie für Das Nebennierenrindenkarzinom - Preclinical Study Towards an Immunotherapy in Adrenocortical Carcinoma

Brief Summary: Adrenocortical carcinoma (ACC) is a rare and heterogeneous malignancy with poor prognosis. Surgical resection of the tumor is the treatment of choice. However, even after complete resection more than 80 % of patients will experience recurrence of disease. Therefore, new treatment options are urgently needed. This pre-clinical study try to lay the foundations for a successful immunotherapy in patients with ACC.

Detailed Summary:
Sponsor: University of Wuerzburg

Current Primary Outcome:

  • To find reasonable antigens for a vaccination therapy in ACC [ Time Frame: day of blood sampling ]
  • To investigate the role of tumor-induced suppression in ACC [ Time Frame: NA, in vitro study ]


Original Primary Outcome:

  • To find reasonable antigens for a vaccination therapy in ACC
  • To investigate the role of tumor-induced suppression in ACC


Current Secondary Outcome:

Original Secondary Outcome:

Information By: University of Wuerzburg

Dates:
Date Received: April 4, 2007
Date Started: September 2005
Date Completion: December 2017
Last Updated: May 7, 2017
Last Verified: May 2017