Clinical Trial: Epidemiology of Acute Respiratory Distress Syndrome in Chinese ICUs

Study Status: Completed
Recruit Status: Unknown status
Study Type: Observational

Official Title: Epidemiology of Acute Respiratory Distress Syndrome in Chinese ICUs

Brief Summary: The acute respiratory distress syndrome(ARDS)has a high morbidity and mortality in patients admitted to intensive care units(ICUs). It represents a significant public health issue. No large nationwide, multicenters study of ARDS has been conducted in China. The purposes of this study are to analyse: 1)the incidence and outcomes of ARDS in ICU; 2) factors associated the mortality ; and 3) risk factors for development of ARDS .

Detailed Summary:

All patients admitted to the participating ICUs during a 6-month period(from January 1, 2015 to July 1,2015 ) will be screened at ICU admission and daily for the occurrence of ARDS ( AECC criteria) for a maximum of 28 days after ICU admission.

Data collection:

  1. For all patients, Demographic characteristics, admission category, the patient source intervention during ICU , APACHEII , SOFA score and discharge information will be collected
  2. For patients with ARDS, data about ABG , parameters of MV, hemodynamic on day0 to day7 and last day of MV will be collected.
  3. For patients without ARDS at ICU admission, data about risk factor for ARDS ,such as LIPS score, parameters of MV , and fluid balance on ICU day0 to day7 will be collected.

Sponsor: Peking Union Medical College Hospital

Current Primary Outcome: incidence of acute respiratory distress syndrome (ARDS) [ Time Frame: from ICU admission to 28-day of ICU stay ]

incidence of ARDS = the number of patients developing ARDS during ICU / the total number of patients admitted to ICU


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • ICU mortality of patients with ARDS [ Time Frame: followed up to 3 months after inclusion or to ICU discharge, whichever occurred first ]
  • hospital mortality of patients with ARDS [ Time Frame: followed up to 3 months after inclusion or to hospital discharge, whichever occurred first ]


Original Secondary Outcome: Same as current

Information By: Peking Union Medical College Hospital

Dates:
Date Received: May 18, 2015
Date Started: January 2015
Date Completion: October 2015
Last Updated: July 1, 2015
Last Verified: May 2015