Clinical Trial: Assessing How Normal Variations in CT Scanning Affects Its Interpretation

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Stability of Radiomic Features for Abdominal Tumors on Contrast Enhanced CT

Brief Summary: The purpose of the study is to see how measurements of tumor differences vary with slight changes in CT scan parameters. Reproducible radiomic features can be extracted for abdominal tumors, and specifically colorectal liver metastases, imaged with clinical CT scanners even in the setting of variable scan parameters and variable contrast timing. Participants will be consented to undergo an additional CT of their abdomen.

Detailed Summary:
Sponsor: Memorial Sloan Kettering Cancer Center

Current Primary Outcome: assess the stability (reproducibility) of radiomic measurements obtained from repeat abdominal CT scans [ Time Frame: 2 years ]

There will be 18 cohorts, each cohort differing by the length of the time gap in acquisition and noise index. In addition each acquisition will be reconstructed in 21 different ways (combinations of 3 slice thicknesses and 7 ASiR levels).


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Memorial Sloan Kettering Cancer Center

Dates:
Date Received: January 30, 2017
Date Started: January 27, 2017
Date Completion: January 27, 2019
Last Updated: April 19, 2017
Last Verified: April 2017