Clinical Trial: Radiofrequency and Chemical Neurolysis of Thoracic Splanchnic Nerve for Abdominal Cancer Pain

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Comparative Study Between Radiofrequency Thermocoagulation and Chemical Neurolysis of Thoracic Splanchnic Nerve Bilaterally for the Management of Abdominal Cancer Pain

Brief Summary: The study compares between the efficacy, safety and impact on the quality of life of radiofrequency thermocoagulation and chemical neurolysis of bilateral thoracic splanchnic nerves in the management of refractory pain which developed in patients suffering from upper abdominal cancer.

Detailed Summary: Radiofrequency thermocoagulation of splanchnic nerves was done bilaterally at level of thoracic vertebra T10 and T11 ( there were no enough studies done to test the efficacy, safety and impact on the quality of life of radiofrequency thermocoagulation of splanchnic nerves at level of T10 ). Aim of the Study is to compare between the efficacy, safety and impact on the quality of life of radiofrequency thermocoagulation of bilateral thoracic splanchnic nerves at level T10 and T11 vertebra and chemical neurolytic block of them at level of T11 vertebra only in the management of upper abdominal cancer pain.
Sponsor: South Egypt Cancer Institute

Current Primary Outcome: Pain relief [ Time Frame: 3 months ]

Visual analogue pain scale


Original Primary Outcome: Same as current

Current Secondary Outcome: Decrease the need for analgesic drugs [ Time Frame: 3 months ]

Reduction of total oral morphine consumption dose in mg per day


Original Secondary Outcome: Same as current

Information By: South Egypt Cancer Institute

Dates:
Date Received: February 10, 2017
Date Started: October 1, 2016
Date Completion: May 1, 2017
Last Updated: February 26, 2017
Last Verified: February 2017