Clinical Trial: Evaluation of Pcv-aCO2 in the Fluid Treatment of Abdominal Tumor Patients After Surgery

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Clinical Study of Central Venous-to-Arterial Carbon Dioxide Difference(Pcv-aCO2) in the Evaluation of Fluid Therapy for Postoperative Patients With Abdominal Cancer

Brief Summary: This research will confirm that Pcv-aCO2 is suitable for the guidance of early fluid therapy and the evaluation of the prognosis of patients with abnormal hemodynamics after abdominal tumor surgery, and is expected to be a new monitoring index to improve the therapeutic effect of these patients.

Detailed Summary:

  1. Confirmed that Pcv-aCO2 is suitable for the guidance of early fluid therapy and the evaluation of the prognosis of patients with abnormal hemodynamics after abdominal tumor surgery, and is expected to be a new monitoring index to improve the therapeutic efficacy of this kind of patients.
  2. Pcv-aCO2 effectively reflected the improvement of tissue and organ microcirculation disorder through the individual goal target treatment to guide the fluid resuscitation in the hemodynamic instability patients.
  3. Research of the correlation between Pcv-aCO2 and the organ function in patients with abnormal hemodynamics after operation.

Sponsor: Tianjin Medical University Cancer Institute and Hospital

Current Primary Outcome: The change of Pcv-aCO2 [ Time Frame: fluid resuscitation for 6 hours, 12 hours and 24 hours ]

The change of Pcv-aCO2 (mmHg) after fluid resuscitation for 6 hours, 12 hours and 24 hours respectively.


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • The treatment success rate in different groups [ Time Frame: Twenty-eighth days after admission ]
    Collect the index of treatment success rate(%) of patients in different groups.
  • The 28 day mortality in different groups [ Time Frame: Twenty-eighth days after admission ]
    Collect the index of 28 day mortality(%) of patients in different groups.
  • The hospitalization course in different groups [ Time Frame: Twenty-eighth days after admission ]
    Collect the index of hospitalization course(days) of patients in different groups.


Original Secondary Outcome: Same as current

Information By: Tianjin Medical University Cancer Institute and Hospital

Dates:
Date Received: October 9, 2016
Date Started: October 2016
Date Completion: September 2018
Last Updated: November 27, 2016
Last Verified: October 2016